Accendatech’s
leading portfolio drug is ACT001 that is currently in different stages of
clinical study for multiple indications including brain metastasis, high grade gliomas
such as DMG/DIPG and GBM and inflammatory diseases such as IPF/ILD and
NMOSD. ACT001 is the first-in-class
therapeutics as a dual inhibitor targeting both the NF-κB and STAT3 pathways that are involved in many
pathological processes. The safety
profile of ACT001 has been demonstrated by an array of clinical studies in
adults and pediatric patients. ACT001 has been granted Orphan Drug Designation
from US FDA and European Medicine Authority as brain tumor therapy. It was also granted the Pediatric Rare Disease
Designation and Fast Track Designation from FDA as a potential therapy for patients
with DMG/DIPG.
Accendatech is actively seeking partnership for co-development or licensing to accelerate the development of ACT001 that could benefit to patients globally. Further business development discussion could be directed to info@accendatech.com